TP53 and metastatic neoplasm: These tumors are also positive for known markers for ovarian cancer, such as Wilms tumor 1 (WT1), p53, Ki-67 (MIB-1), and CA-125 (MUC16), and are positive for the epithelial marker cytokeratin 14 (KRT14) in both primary and metastatic tumor tissues (Fig 1B; S1A Fig).