The data illustrated that the factors of cycles with > 80% MII oocytes were not significantly related to age, BMI, and infertility duration (P > 0.05), nor with the oocyte trigger method [GnRH agonist as reference (ref.); hCG group: odds ratio (OR) 1.234, 95% confidence interval (CI) 0.803–1.896, P > 0.05; dual trigger group: OR 1.082, 95% CI 0.719–1.629, P > 0.05]. This evidence concerns the gene GNRH1 and Infertility.