Since the numbers of PCOS women with MetS were only 14 people and it would be underpowered in comparison with 137 PCOS women without MetS, 28 age- and BMI-matched participants out of 137 PCOS women without MetS were selected and the androgenic components (TT, FAI, and SHBG) were compared between these two groups. The gene discussed is SHBG; the disease is polycystic ovary syndrome.