Having demonstrated that CMV infection of CD14+/16− monocytes mediates deficits in phagocytosis (immunosuppressive phenotype) and induction of the inflammasome and pro-inflammatory mediators of allograft rejection ( immunostimulatory phenotype), with similar results in CD14+/16+ monocytes (table S4), we used single-cell RNA sequencing (scRNA-Seq) to understand the heterogeneity of these responses in CMV-infected monocytes. Here, CD14 is linked to cytomegalovirus infection.