In CMV-infected monocytes, there was simultaneous induction of expression of viral PRR genes TLR3 (logFC = 3.9, FDR = 7.4 × 10−9) and TLR7 (logFC = 1.8, FDR = 0.003) (32–34) and inhibition of expression of TLR6 (logFC = −1.78, FDR = 0.01) (Fig. 3H), the latter of which has been shown to partner with TLR2 in the recognition of C. albicans and prevention of disseminated candidiasis and confer risk to developing invasive aspergillosis (35, 36). Here, TLR6 is linked to disseminated candidiasis.