Another study conducted in Germany, showed polymorphism of IL-1B gene was without any involvement of carcinogenesis.23 A comparative study investigated the haplotype frequencies (CC, TC and TT) in four Asian populations with gastric diseases and found Japan and Thailand population at higher risk of H. pylori infection as compared with China and Vietnamese population.24 In the present study, a potential association of allelic variants of IL-1B gene with gastritis was found. This evidence concerns the gene IL1B and stomach disorder.