Two studies on osteosarcoma supported that high TP73-AS1 expression was notably associated with advanced clinical stage (OR = 3.184, 95% CI 1.732-5.854) and distant metastasis (OR = 4.730, 95% CI 2.225-10.053) but not with tumor site (OR = 0.650, 95% CI 0.309-1.366). The gene discussed is TP73; the disease is osteosarcoma.