WT1 and disorder of sexual differentiation: The variant in ZF3 (p.Gln437Lys), which is not associated with DSD in XX individuals, showed a low level of interaction with the β-CATENIN protein that is comparable to the WT1-WT (SI Appendix, Fig. S6), suggesting that the stronger interaction of WT1 proteins with β-CATENIN is a unique property of ZF4 mutants.