Nerve conduction studies classically demonstrate an axonal pattern of injury; however, the possibility of nerve conduction studies in the demyelinating range has been described in late onset TTR-FAP.4–6 Other common symptoms involve autonomic disturbance and extra-neurological manifestations such as cardiomyopathy, vitreous involvement, and progressive renal failure.1 Death within 10 years is believed to be the usual outcome.3 The gene discussed is TTR; the disease is cardiomyopathy.