NOTCH1 and Stroke: Preventing the cleavage of Notch1 into the NICD by N-[N-(3,5-difluorophenacetyl-l-alanyl)]-S-phenylglycine t-butyl ester (DAPT, a γ-secretase inhibitor) augments the regeneration of motor neurons in the injured spinal cords of zebrafish [49] and promotes endogenous neurogenesis and axonal reorganization in a rat stroke model [48].