We confirmed the ability of circSATB2 to regulate FSCN1 via miR-326 by detecting FSCN1 expression in circSATB2 knockdown or overexpressing NSCLC cells via qPCR and found that FSCN1 expression was positively regulated by circSATB2. The gene discussed is FSCN1; the disease is non-small cell lung carcinoma.