EFS, RFS and CIR were inferior in CD56+ APL (66.1% vs. 83.1%, p = 0.007, 76.5% vs. 91.4%, p = 0.005, HR 3.04 (1.34–6.90) and 23.5% vs. 8.1%, p = 0.004, HR 3.34 (1.45–7.69, respectively) than for CD56− APL, while OS was not significantly different between the two groups (78.9% vs. 89.4%, p = 0.069) (Figure 3). The gene discussed is NCAM1; the disease is acute promyelocytic leukemia.