Studies included in a meta-analysis by Tian X et al. [7], investigating the TP53 rs1042522 on AML patients [1,12,13,14,15], did not find associations between the variant genotypes of TP53 rs1042522 and AML susceptibility, except the study performed by Dunna NR et al. [16] on 141 Japanese AML patients. This evidence concerns the gene TP53 and acute myeloid leukemia.