Recently, in other types of cancer, the variant genotypes of MDM2 rs2279744 and/or rs3730485 were reported as risk factors for breast cancer but with a trend towards a good prognosis [48], for laryngeal [49], gynecological cancers [50], and in haplotype analysis for papillary thyroid carcinoma [17]. Here, MDM2 is linked to thyroid gland papillary carcinoma.