Our model identified a series of features related to progressive respiratory failure (respiratory rate, oxygen saturation), markers of systemic inflammation (C-reactive protein, white blood cell count), shock (systolic and diastolic blood pressures), renal failure (blood urea nitrogen, anion gap, and serum creatinine), and the pathophysiology of COVID-19 (lymphocyte count). The gene discussed is CRP; the disease is Renal insufficiency.