Furthermore, the increase of ROS triggers a multitude of response in different signaling pathways such as MAPK (Mitogen-activated protein kinase) [111], NF-κB (nuclear factor kappa-light-chain-enhancer of activated B cells) [112], STAT3 (Signal transducer and activator of transcription 3) [113,114], or PPARγ (Peroxisome proliferator-activated receptor gamma) [115] that promote antioxidant gene expression, proliferation, and survival in response to oxidative stress, which allow cancer cells to progress. Here, STAT3 is linked to cancer.