Several genes and loci, primarily including low-penetrance variants near or in FOXE1, SRGAP1, TITF-1/NKX2-1, DIRC3, and CHEK2, have been suggested to affect susceptibility to non-syndromic FNMTC [2,3]. Here, NKX2-1 is linked to familial papillary or follicular thyroid carcinoma.