TNFSF10 and Sepsis: There was a statistically significant trend of decreased plasma TRAIL level across control, sepsis, and septic shock groups (52.00 [35.66–74.41] pg/mL vs. 35.83 [28.07–60.82] pg/mL vs. 26.08 [15.29–40.97] pg/mL; p < 0.001) (Figure 2).