TACR1 and neoplasm: The glycolytic rate of tumor cells is 200 times higher (known as the Warburg effect) than that observed in normal cells, and consequently, the NK-1R is also needed to obtain glucose and, in the case that the stimulus is blocked by NK-1R antagonists, tumor cells die by apoptotic mechanisms due to starvation and hence an anti-Warburg action occurs [13,64].