To further ascertain whether there were associations between TP53, DDR1, and the RAS/Raf/MEK/ERK cascade in DU145 prostate cancer cells either lacking or containing WT-TP53, the expression of DDR1 was monitored in DU145 and DU145 + WT-TP53 cells (Figure 8). The gene discussed is MAP2K7; the disease is Familial prostate cancer.