MUC16 and melanoma: Besides, we found that male patients with MUC16 mutations had a better OS than those without MUC16 mutations (median OS: not calculable [the median OS of melanoma male patients with MUC16 mutations could not be calculated owing to more than half patients in this group were alive] vs. 20.9 [95% CI, 9.17-NA (not available)] months; Log rank test P = 0.042; Figure 5D).