ATF3 and neuropathy: ATF3 was not increased, nor was there any change in the density of CGRP, and IB4 in small- and large-diameter DRG neurons, which has been observed in nerve injury-induced neuropathy models (Gehrmann et al., 1991, Hu and McLachlan, 2002, Peters et al., 2007), but not in chemotherapy induced neuropathies (Flatters and Bennett, 2006).