The genetic and morphologic commonalities between this tumor and CMNs, as well as the clinical context and possible origin in the kidney, all suggest that the spectrum of this disease may be wider than previously thought, and some poorly-differentiated abdominal neoplasms in infants may in fact be related etiologically to EGFR-mutated CMN, similarly to how ETV6-NTRK3 positive CMN is proposed to be related to IFS. Here, EGFR is linked to neoplasm.