In patients without HF, plasma concentrations of NT-proBNP were comparable between obese and non-obese patients (Estimate: –0.358; T = –1.84; 95%CI –0.739–0.024; P = 0.066), whereas, plasma concentrations of MR-proANP were lower in obese patients (Estimate: –0.242; T = –2.74; 95%CI –0.415–0.069; P = 0.006), and plasma concentrations of MR-proADM (0.195; T = 4.28; 0.105; 95%CI 0.105–0.285; P < 0.001) and copeptin (Estimate: 0.380; T = 3.11; 95%CI 0.140–0.620; P = 0.002) were higher in obese patients (Figure 2A–D). The gene discussed is NPPA; the disease is hydrops fetalis.