CCL11 and Pseudoxanthoma elasticum: As seen in Fig. 1, means of serum concentration of CCL11 increased significantly with age in PXE patients (<45 years: 135.4 ± 10.6 pg/ml; >45 years: 207.8 ± 22.9 pg/ml; p≤0.01) as well as in healthy controls (<45 years: 158.9 ± 13.0 pg/ml; >45 years: 231.7 ± 21.8 pg/ml; p≤0.01).