It is postulated that the intense inflammation observed in the lung parenchyma (ARDS) is due to an inflammatory cascade characterized by elevation of Interleukin1 (IL-1), tumor necrosis factor 1 (TNF-1alfa) and interleukin 6 (IL-6) produced by inflammatory macrophage M1 [4]. The gene discussed is IL6; the disease is acute respiratory distress syndrome.