VEGFA and neoplasm: 31, 338, 339 Patients that had higher than normal levels at baseline were reported to have a poorer prognosis and an increased treatment effect of bevacizumab when compared with patients with low levels. 31,338 The proposal that VEGF level, in serum or tumor biopsies, could fulfill the requirements of a predictive biomarker has so far remained inconclusive. 340,341