Patients with age ≥60 (57.0%), colon cancer (66.4%), low tumor grade (63.1%), tumor size ≥5 cm (58.5%), adenocarcinoma (84.8%), CEA positive (81.3%), high AJCC T stage (85.4%) or lymph node metastasis positive (77.2%) had higher proportion. This evidence concerns the gene CEACAM5 and adenocarcinoma.