HMGA2 and squamous cell carcinoma: Moreover, HMGA2 expression is associated with a more malignant phenotype and a poor prognosis in squamous carcinomas of the oral cavity [31], nasopharyngeal carcinomas [32], glioblastoma [33], esophageal squamous carcinoma [34], lung cancer [35], and atypical teratoid/rhabdoid tumor [36].