In an attempt to achieve a more consistent classification of SRC-GC, a multidisciplinary expert panel recently proposed specific cut-off values for the percentage of SRCs to distinguish bona-fide SRC-GC (more than 90% SRCs) from poorly cohesive GC with SRC component (between 10 and 90% SRCs) and poorly cohesive GC not otherwise specified (less than 10% SRCs) [25]. Here, SRC is linked to gastric cancer.