The chemopreventive role of dietary components in CRC, such as resveratrol, curcumin, quercetin, α-mangostin, ω-3-polyunsaturated fatty acids, vitamin D and dietary fiber has been reported to occur through the modulation of epigenetic regulators affecting cell proliferation/apoptosis, activating tumor suppressor genes (p53 and PTEN), and inducing ROS-mediated cytotoxicity32. Here, TP53 is linked to colorectal carcinoma.