Although the present study did not determine which protein types were involved in proteinuria, the subtle increase in UP/CR values (>0.15) and the reduction in albumin (<2.94 g/dL) correlated significantly with the degree of tubular degeneration, acute tubular necrosis, inflammatory infiltrate and membranoproliferative glomerulonephritis (Table 4), corroborating with glomerular and tubular impairment. The gene discussed is ALB; the disease is membranoproliferative glomerulonephritis.