In conclusion, AKI is a very prevalent condition in patients with sepsis, derived mainly from changes in renal perfusion and inflammation and reflected by clinical, haematological, urinary, and ultrasonographic variables: RLeng/AorRatio >5.93, pulsatility index >1.53, TaMin <21.5 cm/s, TaMax <45.7 cm/s, and CortPeak <69%, with regard to perfusion changes, and UP/CR > 0.15 and serum albumin <2.94 mg/dL, with regard to inflammatory alteration. The gene discussed is ALB; the disease is Sepsis.