Most deletions in prostate cancer are linked to either ERG negative cancers (i.e., deletions of 5q, 6q, 13q, 18q) or ERG positive cancers (i.e., deletions of 3p, 8p, 10q (PTEN), 12q, 16q, 17q). The gene discussed is PTEN; the disease is Familial prostate cancer.