For example, in more than 90 studies published in Pubmed as to yet (March 2020), up regulation of YAP1 was reported from cancers of the cervix6, endometrium7, oesophagus8, urinary bladder9, brain10,11, skin12, head and neck13, ovary14, mesothelium15, bones16, lung17, breast18, colon19, stomach20, pancreas21 and liver22, and was linked to adverse tumour features and/or poor patient prognosis in most tumour types. The gene discussed is YAP1; the disease is cancer.