We therefore examined secretome profiles of tumour-conditioned (BLM-CM and OMC-CM) and control media (Fb-CM and OSC-CM) (Fig. 5b), and focused our attention on CCL-2, IL-6 and PGE2, factors known to play a role in tumour modulation of myeloid functions30–32. The gene discussed is IL6; the disease is neoplasm.