About 40% of cbsa morphants developed morphologically abnormal eyes: a small proportion of these completely lacked eyes and the remainder had reduced eyes compared to those injected with control MO, including ventrally displaced lenses with decreased expression of the lens marker gene cryaa (Fig. 6a, b; Supplementary Table 3; Supplementary Fig. 4g, h), which is similar to the CF eye phenotype2–5. Here, CRYAA is linked to cystic fibrosis.