At the time of hypertension diagnosis or the last encounter (for those who did not develop hypertension), a lower recent CD4+/CD8+ ratio (aHR 0.14, 95% CI: 0.06–0.31, p < 0.001) and a higher recent VL (aHR 1.28, 95% CI: 1.08–1.51, p < 0.01) were also associated with incident hypertension (Fig. 2). Here, CD8A is linked to hypertensive disorder.