Recently, a whole exome sequencing performed on 12 adenoid cystic carcinomas demonstrated that no somatic mutations in TP53, PIK3CA, RB1, BRCA1 or BRCA2 genes were identified in breast adenoid cystic carcinomas, unlike what occurs in common-type triple-negative and basal-like breast cancers. The gene discussed is PIK3CA; the disease is adenoid cystic breast carcinoma.