LNC13 is a recently characterized lncRNA that is involved in the inhibition of pro-inflammatory gene expression in macrophages and associated with susceptibility to celiac disease (CeD).64 The LNC13 locus is located on chromosome 2 in proximity to the pro-inflammatory gene IL18RAP and its RNA forms a complex with HNRNPD, a ubiquitously expressed heterogeneous nuclear ribonucleoprotein and the histone deacetylase enzyme HDAC1. Here, IL18RAP is linked to cranioectodermal dysplasia.