Moreover, DSCAM-AS1 expression is elevated in tamoxifen-resistant breast cancer tissues, and the knockdown and overexpression experiments of DSCAM-AS1 in breast cancer cell lines, such as MCF7 and T47D, suggest that DSCAM-AS1 promotes tamoxifen resistance [110,111]. The gene discussed is DSCAM-AS1; the disease is breast carcinoma.