Moreover, CYTOR is upregulated in tamoxifen-resistant breast cancer cell lines derived from MCF7, and CYTOR functions as a ceRNA by sponging miR-125a-5p, and upregulates a target of miR-125a-5p, the serum response factor (SRF), which promotes the tamoxifen resistance and cell proliferation [95]. This evidence concerns the gene SRF and breast carcinoma.