This is not surprising, given that overexpression of Gal-3 can promote properties associated with stemness, including chemoresistance [31,89,90,123], enhanced sphere or colony-forming capacity [88], enhanced DNA damage response [124], increased tumorigenesis [125], etc. Consequently, Kang and colleagues [88] assessed multiple ovarian cancer cell lines for their capacity to form spheres. The gene discussed is LGALS3; the disease is ovarian carcinoma.