The presence of all remaining antibiotic resistance genes mostly detected in MRSA, but sporadically also found in MSSA (aacA-aphD, aadD, blaI/R/Z, dfrS1, ermA/B/C, and fosB), most likely results from the application of tobramycin, kanamycin, penicillins, trimethoprim, erythromycin, and fosfomycin to CF patients or livestock animals. The gene discussed is TMEM94; the disease is cystic fibrosis.