On the contrary, obstructive azoospermia with bilateral congenital absence of vas deferens (CBAVD) (generally, low semen volume and pH, normal testicular volume, normal reproductive hormones, no evidence of vas deferens by palpation, and scrotal and transrectal ultrasonography) should be tested for cystic fibrosis transmembrane conductance regulator (CFTR) gene mutations (including the 5Tallele) [1,21,22,23,24,27,28]. This evidence concerns the gene CFTR and Azoospermia.