CXCL10 and infection: In contrast, there were increased IP-10 levels in the lungs of Ad14p1-infected hamsters detected beginning at day 1 p.i. and peaking at days 7 and 10 p.i., before returning to the low levels observed with Ad14 infection by day 14 p.i. In summary, these data show that infection with both viruses induced cytokine and chemokine responses greater than the baseline levels detected in uninfected hamsters and, more importantly for this comparative immunopathological study, that there was a generally greater cytokine and chemokine response to infection with Ad14p1 than to infection with Ad14.