PINK1 and pulmonary fibrosis: Interestingly, in mice models of bleomycin-induced pulmonary fibrosis, increased susceptibility to lung fibrosis was found secondary to PINK1 deletion, in addition to dysfunctional mitochondria and protein aggregation in the endoplasmic reticulum (ER), suggesting a link between mitochondria function and proteostasis alteration in the pathogenesis of this disease [77,81].