Patients who had a stroke during the follow up did not show a significant decrease in Gal-3 concentration, whereas patients without a history of stroke revealed a statistically significant reduction in Gal-3 concentration on the follow-up visit (12.2 ± 6.7 ng/mL vs. 8.7 ± 2.4 ng/mL, p = 0.0002). Here, LGALS3 is linked to Stroke.