Hsu et al. found no statistical differences in several parameters (fasting glucose, insulin, HOMA-IR, HbA1c, lipoproteins, hormones (leptin, ghrelin, adiponectin), blood pressure, anthropometrics) between a decaffeinated GTE-supplemented group (3 × 500 mg/day; 856 mg EGCG) of T2D obese patients and the placebo group. Here, INS is linked to type 2 diabetes mellitus.