Dyslipidemia (p = 0.041, HR = 3.08, 95% I.C. = 1.05: 9.09), age at baseline (p = 0.001, HR = 1.16, 95% I.C. = 1.07:1.27) and ApoE ε4 (p = 0.001, HR = 6.21, 95% I.C. = 2.04:18.9) were statistically significantly associated with an increased likelihood of conversion to AD (Table 4). This evidence concerns the gene APOE and metabolic syndrome.