Finally, we ranked the whole sample according to history of dyslipidemia and ApoE genotype (non-dyslipidemic/ε4−, n = 29; non-dyslipidemic/ε4+, n = 17; dyslipidemic/ε4−, n = 15; dyslipidemic/ε4, n = 4) and Kaplan–Meier survival analysis was conducted to compare the proportions of conversions in the four different groups. The gene discussed is APOE; the disease is metabolic syndrome.