ACE and Stroke: A recent post hoc analysis of the TECOS CV outcomes trial of the dipeptidyl peptidase-4 inhibitor sitagliptin found that attainment of 5 risk factor measures at baseline (aspirin use, LDL cholesterol <70 mg/dL or statin use, SBP/DBP <140/<90 mmHg, use of ACE inhibitor or angiotensin II receptor blocker, nonsmoking) was associated with reduced risk for CV death, MI, and stroke in T2D patients with established CV disease (18).