Among the Sp and SpOc lincRNAs and PCGs, Sp-lincRNAs from sperm-derived chromatin cluster high-K4 showed more aberrant expression compared with the Sp-lincRNAs from low-K4 and K4-K27- clusters (Figure 8A); thus, the level of their deregulation in cancers correlated with the extent of H3K4me3 enrichment at their promoters. This evidence concerns the gene KRT4 and cancer.