At present, patients with NR2F1 haploinsufficiency are diagnosed for the Bosch‐Boonstra‐Schaaf optic atrophy syndrome (BBSOAS), an emerging neurodevelopmental autosomal dominant disorder (OMIM #615722; ORPHANET #401777) leading to a broad range of clinical phenotypes associated with visual and cognitive deficits reviewed in Bertacchi et al (2018). Here, NR2F1 is linked to Cognitive impairment.