NR2F1 and Global developmental delay: In the last few years, deletion and point mutations in the NR2F1 locus have been identified in patients with optic nerve atrophy associated with developmental delay, autistic features, epilepsy, and ID (Brown et al, 2009; Cardoso et al, 2009; Al‐Kateb et al, 2013; Bosch et al, 2014; Chen et al, 2016, 2017; Kaiwar et al, 2017; Martín‐Hernández et al, 2018).