TRPM4 and breast cancer: In The Cancer Genome Atlas (TCGA) breast cancer cases as curated by Gene Expression Profiling Interactive Analysis 2 database (http://gepia2.cancer-pku.cn/) [44], TRPM4 transcript levels were significantly higher in breast cancer cases (n = 1,085) compared with normal breast tissues (n = 112) (p = 1.03 x 10−11) (Fig 1B).