TRPM4 and ductal breast carcinoma in situ: All DCIS cases (n = 6) expressed TRPM4 with median and mean frequency of 50% and 60%, respectively, and weak (n = 3/6; 50%), moderate (n = 1/6; 16.7%) or strong (n = 2/6; 33.3%) intensity (Fig 4K and 4L).