TRPM4 and breast carcinoma: Half of the NBT cases (n = 5/10; 50%) were negative for TRPM4 (Fig 4B and 4C), and TRPM4 protein was significantly overexpressed in breast cancers (n = 83/99 TRPM4+; 83.8%) compared with normal breast ducts (n = 5/10 TRPM4+; 50%) (p = 0.022).