MKI67 and neoplasm: Out of all investigated immune cell markers, proliferation and nuclear features, clinical and histopathological parameters only Ki67 (threshold 39%, HR: 0.61, 95% CI, 0.4-0.9; p = 0.05) and Multifocality (HR: 1.8, 95% CI, 1.2-2.7; p = 0.01) showed significant association with tumor recurrence.